Molecular Regulation of Histamine Synthesis
نویسندگان
چکیده
1Hua Huang, Department of Biomedical Research, National Jewish Health, Denver, CO, USA 2Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO, USA 1Yapeng Li, Department of Biomedical Research, National Jewish Health, Denver, CO, USA 1Jinyi Liang, Department of Biomedical Research, National Jewish Health, Denver, CO, USA 3Department of Parasitology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China 4Fred D. Finkelman, the Division of Immunobiology, Cincinnati Children's Hospital Medical Center, 5The Division of Immunology, Allergy and Rheumatology, Department of Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
منابع مشابه
Interaction of intracerebroventricular injection of captopril and histamine on water intake in adult male Wistar rats
Several evidences have indicated that many nuclei in the brain have critical role in water intake. Angiotensin II is one of the most important neurotransmitters involved in regulation of fluid homeostasis. In this study, the interaction of i.c.v. injection of captopril and histamine on water intake in adult male water-deprived rats was investigated. Rats were implanted with guide cannula aimed ...
متن کاملH3 autoreceptors modulate histamine synthesis through calcium/calmodulin- and cAMP-dependent protein kinase pathways.
H(3) autoreceptors provide feedback control of neurotransmitter synthesis in histaminergic neurons, but the transduction pathways involved are poorly understood. In rat brain cortical slices, histamine synthesis can be stimulated by depolarization and inhibited by H(3) agonists. We show that histamine synthesis stimulation by depolarization with 30 mM K(+) requires extracellular calcium entry, ...
متن کاملPresynaptic H3 autoreceptors modulate histamine synthesis through cAMP pathway.
Histamine H3 receptors modulate histamine synthesis, although little is known about the transduction mechanisms involved. To investigate this issue, we have used a preparation of rat brain cortical miniprisms in which histamine synthesis can be modulated by depolarization and by H3 receptor ligands. When the miniprisms were incubated in presence of forskolin, dibutyryl-cAMP, or 3-isobutyl-1-met...
متن کاملHistamine-neurotrophin-3 interactions in cultured rat astrocytes
Background Neurotrophin-3 (NT-3) is produced by astrocytes, in addition to neurons, and monoamine neurotransmitters play a role in controlling NT-3 synthesis [1]. The impact of histamine on the regulation of NT-3 synthesis in cultured astrocytes has not been studied in detail. Therefore, we focused our present study on the active involvement of multiple histaminergic receptor and intracellular ...
متن کاملA 61 Histamine – neurotrophin - 3 interactions in cultured rat astrocytes
Background Neurotrophin-3 (NT-3) is produced by astrocytes, in addition to neurons, and monoamine neurotransmitters play a role in controlling NT-3 synthesis [1]. The impact of histamine on the regulation of NT-3 synthesis in cultured astrocytes has not been studied in detail. Therefore, we focused our present study on the active involvement of multiple histaminergic receptor and intracellular ...
متن کاملInteraction of intracerebroventricular injection of captopril and histamine on water intake in adult male Wistar rats
Several evidences have indicated that many nuclei in the brain have critical role in water intake. Angiotensin II is one of the most important neurotransmitters involved in regulation of fluid homeostasis. In this study, the interaction of i.c.v. injection of captopril and histamine on water intake in adult male water-deprived rats was investigated. Rats were implanted with guide cannula aimed ...
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